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Publication : The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.

First Author  Nagarajan L Year  1986
Journal  Proc Natl Acad Sci U S A Volume  83
Issue  17 Pages  6568-72
PubMed ID  3529088 Mgi Jnum  J:8408
Mgi Id  MGI:56875 Doi  10.1073/pnas.83.17.6568
Citation  Nagarajan L, et al. (1986) The human c-ros gene (ROS) is located at chromosome region 6q16----6q22. Proc Natl Acad Sci U S A 83(17):6568-72
abstractText  The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone has been used to map the human c-ros homolog (ROS) to human chromosome region 6q16----6q22 by somatic cell hybrid analysis and chromosomal in situ hybridization. Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies.
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