First Author | Nagarajan L | Year | 1986 |
Journal | Proc Natl Acad Sci U S A | Volume | 83 |
Issue | 17 | Pages | 6568-72 |
PubMed ID | 3529088 | Mgi Jnum | J:8408 |
Mgi Id | MGI:56875 | Doi | 10.1073/pnas.83.17.6568 |
Citation | Nagarajan L, et al. (1986) The human c-ros gene (ROS) is located at chromosome region 6q16----6q22. Proc Natl Acad Sci U S A 83(17):6568-72 |
abstractText | The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone has been used to map the human c-ros homolog (ROS) to human chromosome region 6q16----6q22 by somatic cell hybrid analysis and chromosomal in situ hybridization. Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies. |