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Publication : Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas.

First Author  Villeneuve L Year  1986
Journal  Mol Cell Biol Volume  6
Issue  5 Pages  1834-7
PubMed ID  3785181 Mgi Jnum  J:8501
Mgi Id  MGI:56967 Doi  10.1128/mcb.6.5.1834
Citation  Villeneuve L, et al. (1986) Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas. Mol Cell Biol 6(5):1834-7
abstractText  Two loci independently implicated in T-and B-lymphocyte neoplasia are shown to be equivalent. The Mis-1 locus is a common proviral integration site in retrovirally induced rat T lymphomas, while the pvt-1 locus on murine chromosome 15 frequently translocates to the kappa locus in plasmacytomas bearing 6;15 translocations. By comparing cloned sequences, we show that pvt-1 is the murine homolog of Mis-1.
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