First Author | Dildrop R | Year | 1987 |
Journal | Eur J Immunol | Volume | 17 |
Issue | 5 | Pages | 731-4 |
PubMed ID | 3034625 | Mgi Jnum | J:8717 |
Mgi Id | MGI:57182 | Doi | 10.1002/eji.1830170525 |
Citation | Dildrop R, et al. (1987) A new V gene expressed in lambda-2 light chains of the mouse. Eur J Immunol 17(5):731-4 |
abstractText | We have partially sequenced the light chain variable regions expressed in three IgM-producing hybridomas generated from newborn mice or from manipulated animals suppressed for IgM production. In these lines a new V gene (V-lambda-X), exhibiting less than 60% homology to any known lambda or kappa V gene, is rearranged to J-lambda-2. The light chains produced by these cells contain the lambda-2 constant domain, but are not recognized by goat antisera raised against conventional mouse lambda light chains. |