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Publication : Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha 2u-globulin superfamily.

First Author  Drayna DT Year  1987
Journal  DNA Volume  6
Issue  3 Pages  199-204
PubMed ID  2439269 Mgi Jnum  J:22924
Mgi Id  MGI:71519 Doi  10.1089/dna.1987.6.199
Citation  Drayna DT, et al. (1987) Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha 2u-globulin superfamily. DNA 6(3):199-204
abstractText  The exons and bordering intron nucleotides of the human apolipoprotein D (apo D) gene have been sequenced. The protein-coding portion of the gene is divided into five exons which span approximately 12,000 bp. At least one intron interrupts the 5' untranslated region. The gene has been localized to the p14.2----qter region of human chromosome 3. Apo D shares homology with the alpha 2u-globulin superfamily of genes, including approximately 25% amino acid homology with human retinol-binding protein (RBP). Similarity of intron locations in both apo D and RBP suggests that these two genes derived from a common ancestor.
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