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Publication : Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse.

First Author  Keitges EA Year  1987
Journal  Genetics Volume  116
Issue  3 Pages  465-8
PubMed ID  3475232 Mgi Jnum  J:8799
Mgi Id  MGI:57264 Doi  10.1093/genetics/116.3.465
Citation  Keitges EA, et al. (1987) Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse. Genetics 116(3):465-8
abstractText  Dosage studies and the inheritance pattern of the gene for steroid sulfatase (Sts) in the mouse have previously provided indirect evidence for a functional Y-linked allele which recombines obligatorily with its X-linked allele in male meiosis. In this study, we have investigated the linkage relationship of Sts and the sex-reversed mutation (Sxr), a gene which is known to reside in the pairing region of the Y chromosome. The results clearly demonstrate that Sxr and Sts are linked in a region of obligatory recombination and Sts maps proximal to Sxr with most recombinants occurring proximal to the two genes.
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