| First Author | Reddy ES | Year | 1987 |
| Journal | Proc Natl Acad Sci U S A | Volume | 84 |
| Issue | 17 | Pages | 6131-5 |
| PubMed ID | 3476934 | Mgi Jnum | J:16358 |
| Mgi Id | MGI:64439 | Doi | 10.1073/pnas.84.17.6131 |
| Citation | Reddy ES, et al. (1987) The erg gene: a human gene related to the ets oncogene. Proc Natl Acad Sci U S A 84(17):6131-5 |
| abstractText | We have isolated a cDNA clone representing the complete coding sequence of a human gene named erg, related to the ets oncogene. Nucleotide sequence analysis of this cDNA (4.6 kilobases long) revealed that this gene encodes a 363-residue protein whose predicted amino acid sequence showed a homology of approximately equal to 40% and approximately equal to 70% to two domains corresponding to the 5' and 3' regions of v-ets oncogene, respectively. A 3.2- to 3.6-kilobase and approximately equal to 5-kilobase transcript of the erg gene, which differ in size from those of the previously described Hu-ets 1 and Hu-ets 2 genes, were observed in different cells. These results suggest that the erg gene is a member of the ets oncogene family. |
