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Publication : Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system.

First Author  Thompson CC Year  1987
Journal  Science Volume  237
Issue  4822 Pages  1610-4
PubMed ID  3629259 Mgi Jnum  J:32476
Mgi Id  MGI:79972 Doi  10.1126/science.3629259
Citation  Thompson CC, et al. (1987) Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science 237(4822):1610-4
abstractText  A complementary DNA clone derived from rat brain messenger RNA has been isolated on the basis of homology to the human thyroid hormone receptor gene. Expression of this complementary DNA produces a high-affinity binding protein for thyroid hormones. Sequence analysis and the mapping of this gene to a distinct human genetic locus indicate the existence of multiple human thyroid hormone receptors. Messenger RNA from this gene is expressed in a tissue-specific fashion with highest levels in the central nervous system.
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