|  Help  |  About  |  Contact Us

Publication : The locus controlling liver GM1(NeuGc) expression is mapped 1 cM centromeric to H-2K.

First Author  Sakaizumi M Year  1988
Journal  Immunogenetics Volume  27
Issue  1 Pages  57-60
PubMed ID  3334724 Mgi Jnum  J:8929
Mgi Id  MGI:57394 Doi  10.1007/BF00404445
Citation  Sakaizumi M, et al. (1988) The locus controlling liver GM1(NeuGc) expression is mapped 1 cM centromeric to H-2K. Immunogenetics 27(1):57-60
abstractText  The polymorphic variation of liver GM1 (NeuGc) ganglioside was found in inbred strains of the mouse. The genetic analysis using C57BL/10 (GM1-negative) and SWR (GM1-positive) mice revealed that a single autosomal gene (Ggm-1) was involved in the expression of liver GM1(NeuGc) and that C57BL/10 mice lacking GM1(NeuGc) expression carried a defective gene on Ggm-1. Since our previous study on H-2 congenic mice indicated that Ggm-1 was linked to the H-2 complex, in this study we measured recombination frequencies among Ggm-1, Glo-1 and H-2K in the backcross progeny between (C57BL/10 X SWR)F1 and C57BL/10. Ggm-1 was mapped 1 cM centromeric to H-2K on chromosome 17.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

6 Bio Entities

0 Expression