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Publication : The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.

First Author  Ingvarsson S Year  1987
Journal  Cytogenet Cell Genet Volume  45
Issue  3-4 Pages  174-6
PubMed ID  3691183 Mgi Jnum  J:8951
Mgi Id  MGI:57416 Doi  10.1159/000132450
Citation  Ingvarsson S, et al. (1987) The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7. Cytogenet Cell Genet 45(3-4):174-6
abstractText  Mouse Pvt-1 and rat MIS1 are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6;15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-1/MIS1 locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protooncogene and the MIS1/Pvt-1 locus.
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