| First Author | MacLeod AR | Year | 1988 |
| Journal | Mol Cell Biol | Volume | 8 |
| Issue | 1 | Pages | 433-40 |
| PubMed ID | 3336363 | Mgi Jnum | J:20239 |
| Mgi Id | MGI:68347 | Doi | 10.1128/mcb.8.1.433 |
| Citation | MacLeod AR, et al. (1988) Human hTM alpha gene: expression in muscle and nonmuscle tissue. Mol Cell Biol 8(1):433-40 |
| abstractText | We have isolated a cDNA clone from a human skeletal muscle library which contains the complete protein-coding sequence of a skeletal muscle alpha-tropomyosin. This cDNA sequence defines a fourth human tropomyosin gene, the hTM alpha gene, which is distinct from the hTMnm gene encoding a closely related isoform of skeletal muscle alpha-tropomyosin. In cultured human fibroblasts, the hTM alpha gene encodes both skeletal-muscle- and smooth-muscle-type alpha-tropomyosins by using an alternative mRNA-splicing mechanism. |
