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Publication : Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex.

First Author  Elliott E Year  1987
Journal  Gene Volume  61
Issue  2 Pages  189-98
PubMed ID  3443307 Mgi Jnum  J:9093
Mgi Id  MGI:57556 Doi  10.1016/0378-1119(87)90113-2
Citation  Elliott E, et al. (1987) Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex. Gene 61(2):189-98
abstractText  A novel mRNA species is specified by the Q6/Q8 gene, a member of the Qa-2-determining family of class-I genes of the murine major histocompatibility complex. It is longer than all previously described class-I transcripts due to an extension at the 3' end of the mRNA past the predicted polyadenylation site. This mRNA was detected by Northern-blot analyses with single or low-copy-number probes to the 3' end of the Q6/Q8 gene. RNase protection experiments have confirmed this finding. The appearance of this mRNA in different strains of mice correlates with the synthesis of the Qa-2 molecule.
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