First Author | Elliott E | Year | 1987 |
Journal | Gene | Volume | 61 |
Issue | 2 | Pages | 189-98 |
PubMed ID | 3443307 | Mgi Jnum | J:9093 |
Mgi Id | MGI:57556 | Doi | 10.1016/0378-1119(87)90113-2 |
Citation | Elliott E, et al. (1987) Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex. Gene 61(2):189-98 |
abstractText | A novel mRNA species is specified by the Q6/Q8 gene, a member of the Qa-2-determining family of class-I genes of the murine major histocompatibility complex. It is longer than all previously described class-I transcripts due to an extension at the 3' end of the mRNA past the predicted polyadenylation site. This mRNA was detected by Northern-blot analyses with single or low-copy-number probes to the 3' end of the Q6/Q8 gene. RNase protection experiments have confirmed this finding. The appearance of this mRNA in different strains of mice correlates with the synthesis of the Qa-2 molecule. |