| First Author | Kudo A | Year | 1987 |
| Journal | Genomics | Volume | 1 |
| Issue | 3 | Pages | 277-9 |
| PubMed ID | 3128472 | Mgi Jnum | J:9120 |
| Mgi Id | MGI:57583 | Doi | 10.1016/0888-7543(87)90055-3 |
| Citation | Kudo A, et al. (1987) Localization of the murine lambda 5 gene on chromosome 16. Genomics 1(3):277-9 |
| abstractText | The chromosomal location of the murine lambda 5 gene was analyzed by Southern hybridization using restriction enzyme-digested DNA from a panel of 15 mouse X hamster somatic cell hybrids. Sequences homologous with those of lambda 5 DNA were detected in DNA of 5 hybrids. In all 5 hybrids lambda 5 was contained in restriction fragments of equal sizes, the lengths of which indicated that the germline configuration of lambda 5 with three exons and the restriction sites expected from its genomic structure were present. Southern hybridization with the murine lambda 1 gene as a probe detected the same 5 hybrids as positive. The only mouse chromosome present on all of the positive hybrids, and absent from negative ones, was number 16. We conclude that lambda 5 is situated on the same chromosome as lambda 1, i.e., on the murine chromosome 16. |
