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Publication : B-raf, a new member of the raf family, is activated by DNA rearrangement.

First Author  Ikawa S Year  1988
Journal  Mol Cell Biol Volume  8
Issue  6 Pages  2651-4
PubMed ID  3043188 Mgi Jnum  J:31016
Mgi Id  MGI:78325 Doi  10.1128/mcb.8.6.2651
Citation  Ikawa S, et al. (1988) B-raf, a new member of the raf family, is activated by DNA rearrangement. Mol Cell Biol 8(6):2651-4
abstractText  Complementary DNA clones of a putative transforming gene were isolated from NIH 3T3 cells transformed with human Ewing sarcoma DNA. The gene was termed B-raf because it is related to but distinct from c-raf and A-raf. It appears that substitution in the amino-terminal portion of the normal B-raf protein confers transforming activity to the gene.
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