First Author | Ikawa S | Year | 1988 |
Journal | Mol Cell Biol | Volume | 8 |
Issue | 6 | Pages | 2651-4 |
PubMed ID | 3043188 | Mgi Jnum | J:31016 |
Mgi Id | MGI:78325 | Doi | 10.1128/mcb.8.6.2651 |
Citation | Ikawa S, et al. (1988) B-raf, a new member of the raf family, is activated by DNA rearrangement. Mol Cell Biol 8(6):2651-4 |
abstractText | Complementary DNA clones of a putative transforming gene were isolated from NIH 3T3 cells transformed with human Ewing sarcoma DNA. The gene was termed B-raf because it is related to but distinct from c-raf and A-raf. It appears that substitution in the amino-terminal portion of the normal B-raf protein confers transforming activity to the gene. |