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Publication : Regional localization of mouse Abl and Mos proto-oncogenes by in situ hybridization.

First Author  Threadgill DW Year  1988
Journal  Genomics Volume  3
Issue  1 Pages  82-6
PubMed ID  2906048 Mgi Jnum  J:9584
Mgi Id  MGI:58043 Doi  10.1016/0888-7543(88)90164-4
Citation  Threadgill DW, et al. (1988) Regional localization of mouse Abl and Mos proto-oncogenes by in situ hybridization. Genomics 3(1):82-6
abstractText  Two proto-oncogenes, Abl and Mos, have been physically localized on their respective mouse chromosomes by in situ hybridization. By means of Robertsonian translocations to facilitate chromosome identification, Abl was regionally assigned to 2B while Mos was assigned to 4A1-A2. Polymorphisms for these genes have not been reported in genomic DNA from standard inbred strains, nor were they found in this study, thereby prohibiting genetic mapping by meiotic recombination. These physical mapping data, however, extend the number of homologous genes assigned to chromosomal regions in both man and mouse, and better define the segments of conservation on mouse chromosome 2/human chromosome 9 and mouse chromosome 4/human chromosome 8, respectively.
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