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Publication : The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical.

First Author  Koehne CF Year  1989
Journal  J Virol Volume  63
Issue  5 Pages  2366-9
PubMed ID  2704080 Mgi Jnum  J:9706
Mgi Id  MGI:58163 Doi  10.1128/jvi.63.5.2366-2369.1989
Citation  Koehne CF, et al. (1989) The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical. J Virol 63(5):2366-9
abstractText  Mlvi-1 defines a locus of proviral integration in rat thymomas induced by Moloney murine leukemia virus. pvt-1/Mis-1 represents an independently identified locus which becomes rearranged either by chromosomal translocation in murine plasmacytomas or by provirus insertion in retrovirus-induced murine and rat thymic lymphomas. Although it had been claimed that pvt-1/Mis-1 and Mlvi-1 represent two different loci, we present here evidence showing that they are identical. This finding demonstrates the need for rigorous characterization of any newly identified common regions of integration in retrovirus-induced neoplasms.
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