First Author | Toda S | Year | 1989 |
Journal | Jikken Dobutsu | Volume | 38 |
Issue | 2 | Pages | 135-7 |
PubMed ID | 2472970 | Mgi Jnum | J:24618 |
Mgi Id | MGI:72354 | Doi | 10.1538/expanim1978.38.2_135 |
Citation | Toda S, et al. (1989) Strain differences in histamine release from mouse peritoneal mast cells induced by compound 48/80 or A23187. Jikken Dobutsu 38(2):135-7 |
abstractText | Strain differences among BALB/c, BDF1, CDF1, C3 H/He, C57 BL/6, DBA/2, ddy and ICR mice were investigated with respect to the ratios of histamine release from mouse peritoneal mast cells induced by compound 48/80, a Ca2+ dependent histamine releaser, and the Ca2+ ionophore A23187. The ratios of histamine release from mouse peritoneal mast cells induced by compound 48/80 were found to be high in BALB/c, ddY and ICR mice, but low in BDF1, CDF1, C3 H/He, C57 BL/6 and DBA/2 mice. Those induced by Ca2+ ionophore A23187 were high in BALB/c, BDF1, CDF1, C3 H/He, DBA2, ddy and ICR mice but low in C57 BL/6 mice. These results indicate that differences in histamine release from mouse peritoneal mast cells are strain dependent. |