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Publication : Strain differences in histamine release from mouse peritoneal mast cells induced by compound 48/80 or A23187.

First Author  Toda S Year  1989
Journal  Jikken Dobutsu Volume  38
Issue  2 Pages  135-7
PubMed ID  2472970 Mgi Jnum  J:24618
Mgi Id  MGI:72354 Doi  10.1538/expanim1978.38.2_135
Citation  Toda S, et al. (1989) Strain differences in histamine release from mouse peritoneal mast cells induced by compound 48/80 or A23187. Jikken Dobutsu 38(2):135-7
abstractText  Strain differences among BALB/c, BDF1, CDF1, C3 H/He, C57 BL/6, DBA/2, ddy and ICR mice were investigated with respect to the ratios of histamine release from mouse peritoneal mast cells induced by compound 48/80, a Ca2+ dependent histamine releaser, and the Ca2+ ionophore A23187. The ratios of histamine release from mouse peritoneal mast cells induced by compound 48/80 were found to be high in BALB/c, ddY and ICR mice, but low in BDF1, CDF1, C3 H/He, C57 BL/6 and DBA/2 mice. Those induced by Ca2+ ionophore A23187 were high in BALB/c, BDF1, CDF1, C3 H/He, DBA2, ddy and ICR mice but low in C57 BL/6 mice. These results indicate that differences in histamine release from mouse peritoneal mast cells are strain dependent.
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