First Author | White J | Year | 1989 |
Journal | J Immunol | Volume | 143 |
Issue | 6 | Pages | 1822-5 |
PubMed ID | 2778316 | Mgi Jnum | J:27334 |
Mgi Id | MGI:74745 | Doi | 10.4049/jimmunol.143.6.1822 |
Citation | White J, et al. (1989) Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol 143(6):1822-5 |
abstractText | Two variants of the AKR thymoma BW5147 have been isolated which can no longer express functional TCR alpha- and beta-chains. By generating hybridomas with these variant fusion lines, TCR of any normal T lymphocyte, including TCR-gamma/delta, can be studied at a clonal level, without interference of the BW5147-derived receptor chains. In this study one of the variants has been useful in identifying the reactivity to allogeneic MHC Ag of BW5147 itself. |