| First Author | Litt M | Year | 1989 |
| Journal | Genomics | Volume | 5 |
| Issue | 2 | Pages | 204-8 |
| PubMed ID | 2571571 | Mgi Jnum | J:10031 |
| Mgi Id | MGI:58488 | Doi | 10.1016/0888-7543(89)90047-5 |
| Citation | Litt M, et al. (1989) Localization of a human brain sodium channel gene (SCN2A) to chromosome 2. Genomics 5(2):204-8 |
| abstractText | A DNA probe derived from a human genomic library has been used to localize on human chromosomes a gene coding for the alpha-subunit of the brain type II sodium channel (SCN2A). Hybridization of the probe to Southern blots made with DNAs from a rodent-human somatic cell hybrid panel indicates localization to the long arm of human chromosome 2. In situ hybridization to metaphase chromosomes confirms this assignment and indicates regional localization to 2q21-q33. The probe also reveals a frequent two-allele HaeIII RFLP. |
