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Publication : Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.

First Author  Wilkinson DG Year  1989
Journal  Nature Volume  341
Issue  6241 Pages  405-9
PubMed ID  2571936 Mgi Jnum  J:32270
Mgi Id  MGI:79771 Doi  10.1038/341405a0
Citation  Wilkinson DG, et al. (1989) Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341(6241):405-9
abstractText  The vertebrate hindbrain develops in a segmental pattern, with distinctive groups of neurons originating from different segments. We report here that members of the Hox-2 cluster of murine homoeobox genes are expressed in segment-specific patterns in the developing hindbrain, with successive genes having boundaries at two-segment intervals. These data indicate that Hox genes specify segment phenotype, a role analogous to that of their Drosophila homologues.
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