First Author | Wilkinson DG | Year | 1989 |
Journal | Nature | Volume | 341 |
Issue | 6241 | Pages | 405-9 |
PubMed ID | 2571936 | Mgi Jnum | J:32270 |
Mgi Id | MGI:79771 | Doi | 10.1038/341405a0 |
Citation | Wilkinson DG, et al. (1989) Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341(6241):405-9 |
abstractText | The vertebrate hindbrain develops in a segmental pattern, with distinctive groups of neurons originating from different segments. We report here that members of the Hox-2 cluster of murine homoeobox genes are expressed in segment-specific patterns in the developing hindbrain, with successive genes having boundaries at two-segment intervals. These data indicate that Hox genes specify segment phenotype, a role analogous to that of their Drosophila homologues. |