First Author | Board PG | Year | 1989 |
Journal | Ann Hum Genet | Volume | 53 |
Issue | Pt 3 | Pages | 205-13 |
PubMed ID | 2596826 | Mgi Jnum | J:10161 |
Mgi Id | MGI:58617 | Doi | 10.1111/j.1469-1809.1989.tb01786.x |
Citation | Board PG, et al. (1989) Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann Hum Genet 53(Pt 3):205-13 |
abstractText | A partial cDNA clone of the glutathione S-transferase 3 gene (GST3) was obtained by screening a lambda gt11 human lung cDNA library with antiserum to human lung GST3. The sequence of this cDNA showed two base differences from the coding sequence of a GST3 cDNA isolated from a human placental cDNA library. Hybridization of the cloned GST3 cDNA to human chromosomes resulted in a primary peak of grains over band 11q13, a localization predicted by prior experiments. An unexpected strong secondary peak of grains was obtained over bands 12q13 and 12q14, indicating that there is a GST3-like gene on the long arm of chromosome 12 in man. |