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Publication : Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14.

First Author  Board PG Year  1989
Journal  Ann Hum Genet Volume  53
Issue  Pt 3 Pages  205-13
PubMed ID  2596826 Mgi Jnum  J:10161
Mgi Id  MGI:58617 Doi  10.1111/j.1469-1809.1989.tb01786.x
Citation  Board PG, et al. (1989) Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann Hum Genet 53(Pt 3):205-13
abstractText  A partial cDNA clone of the glutathione S-transferase 3 gene (GST3) was obtained by screening a lambda gt11 human lung cDNA library with antiserum to human lung GST3. The sequence of this cDNA showed two base differences from the coding sequence of a GST3 cDNA isolated from a human placental cDNA library. Hybridization of the cloned GST3 cDNA to human chromosomes resulted in a primary peak of grains over band 11q13, a localization predicted by prior experiments. An unexpected strong secondary peak of grains was obtained over bands 12q13 and 12q14, indicating that there is a GST3-like gene on the long arm of chromosome 12 in man.
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