| First Author | Jobs A | Year | 1990 |
| Journal | Hum Genet | Volume | 84 |
| Issue | 2 | Pages | 147-50 |
| PubMed ID | 1967587 | Mgi Jnum | J:10234 |
| Mgi Id | MGI:58688 | Doi | 10.1007/BF00208929 |
| Citation | Jobs A, et al. (1990) Regional assignment of 41 human DNA fragments on chromosome 7 by means of a somatic cell hybrid panel. Hum Genet 84(2):147-50 |
| abstractText | To detect new restriction fragment length polymorphisms that would cover human chromosome 7 with a network of genetic landmarks, a chromosome 7-specific phage gene library was screened for human single-copy fragments. With use of a somatic cell hybrid panel containing defined regions of human chromosome 7, 41 cloned human single-copy sequences were assigned to five regions of this chromosome. Of special importance are the cell hybrid clones GM1059Rag5 and 7851Rag10-1, derived from human cells with interstitial deletions spanning the bands 7q22-q32, within which the cystic fibrosis gene is located. Twelve new probes are described in 7q22-q32, five of which detect a total of six RFLPs. |
