| First Author | Hannum CH | Year | 1990 |
| Journal | Nature | Volume | 343 |
| Issue | 6256 | Pages | 336-40 |
| PubMed ID | 2137200 | Mgi Jnum | J:14588 |
| Mgi Id | MGI:62752 | Doi | 10.1038/343336a0 |
| Citation | Hannum CH, et al. (1990) Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor. Nature 343(6256):336-40 |
| abstractText | Three interleukin-1 inhibitors have been purified to homogeneity from medium conditioned by human monocytes. Partial sequence analysis and digestion with N-glycanase indicate that these are glycosylation forms of a single protein. The protein binds to the interleukin-1 receptor but has no interleukin-1-like activity, even at very high concentrations, and is therefore a pure receptor antagonist. |
