| First Author | Lipkin VM | Year | 1990 |
| Journal | J Biol Chem | Volume | 265 |
| Issue | 22 | Pages | 12955-9 |
| PubMed ID | 2165490 | Mgi Jnum | J:24991 |
| Mgi Id | MGI:72707 | Doi | 10.1016/s0021-9258(19)38252-3 |
| Citation | Lipkin VM, et al. (1990) Beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase. Comparison with the phosphodiesterase family. J Biol Chem 265(22):12955-9 |
| abstractText | A group of cDNA clones encoding the beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase were isolated for structural analysis. The encoded polypeptide has 853 residues with a calculated molecular mass of 98 kDa. The beta-subunit is 72% identical to the rod cGMP phosphodiesterase alpha-subunit. Like the alpha-subunit and the cone alpha'-subunit, the beta-subunit belongs to the family of phosphodiesterase genes. The beta- and alpha-subunits are more similar to each other than either is to the cone alpha'-subunit, suggesting either that the beta- and alpha-subunits diverged more recently or that their divergence was restrained by the rod functional environment. |
