| First Author | Aberdam D | Year | 1991 |
| Journal | Mol Cell Biol | Volume | 11 |
| Issue | 1 | Pages | 554-7 |
| PubMed ID | 1670897 | Mgi Jnum | J:10918 |
| Mgi Id | MGI:59361 | Doi | 10.1128/mcb.11.1.554 |
| Citation | Aberdam D, et al. (1991) The oncogenic potential of an activated Hox-2.4 homeobox gene in mouse fibroblasts. Mol Cell Biol 11(1):554-7 |
| abstractText | The homeobox gene Hox-2.4 is transcriptionally activated in cells of the mouse myeloid leukemia WEHI-3B. The constitutive Hox-2.4 expression in WEHI-3B cells is due to insertion of a transposable element belonging to the family of intracisternal A particles. In this study, we demonstrated the oncogenic potential of this activated homeobox gene. NIH 3T3 fibroblast clones bearing the activated Hox-2.4 gene produced fibrosarcomas in nude mice. |
