| First Author | Joseph DR | Year | 1991 |
| Journal | Cytogenet Cell Genet | Volume | 56 |
| Issue | 2 | Pages | 122-4 |
| PubMed ID | 2013230 | Mgi Jnum | J:11107 |
| Mgi Id | MGI:59549 | Doi | 10.1159/000133064 |
| Citation | Joseph DR, et al. (1991) Genetic mapping of the gene for androgen-binding protein/sex hormone-binding globulin to mouse chromosome 11. Cytogenet Cell Genet 56(2):122-4 |
| abstractText | Southern blot analysis of DNAs from Chinese hamster x mouse and rat x mouse somatic cell hybrids showed that the mouse gene encoding androgen-binding protein/sex hormone-binding globulin (ABP-SHBG) is on Chromosome 11. Progeny from an intersubspecies backcross were analyzed to position this locus, termed Shbg, between Il-3 and Int-4 in the middle of this chromosome. Shbg is thus closely linked to several neurological mutations, one of which, Tr, is also associated with male sterility. The recent finding that ABP-SHBG is found throughout the rat brain raises the possibility that one of these mutations may be due to a defect in Shbg. |
