First Author | De Maeyer-Guignard J | Year | 1991 |
Journal | J Exp Zool | Volume | 258 |
Issue | 2 | Pages | 246-8 |
PubMed ID | 2022949 | Mgi Jnum | J:11148 |
Mgi Id | MGI:59590 | Doi | 10.1002/jez.1402580215 |
Citation | De Maeyer-Guignard J, et al. (1991) Linkage analysis of the murine Hyal-1 locus on chromosome 9. J Exp Zool 258(2):246-8 |
abstractText | We have recently described a new locus, Hyal-1, which determines hyaluronidase variants in mouse serum. On the basis of segregation in recombinant inbred and congenic strains, Hyal-1 was tentatively assigned to chromosome 9 (Fiszer-Szafarz and De Maeyer, '89). In the present study we have performed a linkage analysis of Hyal-1 using 156 backcross progeny of an interspecies cross of laboratory mice and Mus Spretus. Linkage was tested to two anchor loci on chromosome 9: d (dilute, a coat color locus) and Bgl-s (a locus controlling beta-galactosidase activity). The gene order (from centromere) with intervening percentage recombination is d-16.6 (+/- 2.9)-Hyal-1-10.9 (+/- 2.4)-Bgl-s, indicating close linkage to H-7 and Fv-2. |