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Publication : Linkage analysis of the murine Hyal-1 locus on chromosome 9.

First Author  De Maeyer-Guignard J Year  1991
Journal  J Exp Zool Volume  258
Issue  2 Pages  246-8
PubMed ID  2022949 Mgi Jnum  J:11148
Mgi Id  MGI:59590 Doi  10.1002/jez.1402580215
Citation  De Maeyer-Guignard J, et al. (1991) Linkage analysis of the murine Hyal-1 locus on chromosome 9. J Exp Zool 258(2):246-8
abstractText  We have recently described a new locus, Hyal-1, which determines hyaluronidase variants in mouse serum. On the basis of segregation in recombinant inbred and congenic strains, Hyal-1 was tentatively assigned to chromosome 9 (Fiszer-Szafarz and De Maeyer, '89). In the present study we have performed a linkage analysis of Hyal-1 using 156 backcross progeny of an interspecies cross of laboratory mice and Mus Spretus. Linkage was tested to two anchor loci on chromosome 9: d (dilute, a coat color locus) and Bgl-s (a locus controlling beta-galactosidase activity). The gene order (from centromere) with intervening percentage recombination is d-16.6 (+/- 2.9)-Hyal-1-10.9 (+/- 2.4)-Bgl-s, indicating close linkage to H-7 and Fv-2.
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