| First Author | Herman GE | Year | 1991 |
| Journal | Genomics | Volume | 9 |
| Issue | 4 | Pages | 670-7 |
| PubMed ID | 1674728 | Mgi Jnum | J:11194 |
| Mgi Id | MGI:59635 | Doi | 10.1016/0888-7543(91)90360-q |
| Citation | Herman GE, et al. (1991) Genetic mapping of the mouse X chromosome in the region homologous to human Xq27-Xq28. Genomics 9(4):670-7 |
| abstractText | The four loci Gabra3, DXPas8, CamL1, and Bpa, located near the murine X-linked visual pigment gene (Rsvp), have been ordered using 248 backcross progeny from an interspecific mating of (B6CBA-Aw-J/A-Bpa) and Mus spretus. One hundred twenty backcross progeny have been analyzed at seven anchor loci spanning the X chromosome and form a regional mapping panel. An additional 128 progeny have been screened for recombination events between Cf-9 and Dmd. Eighteen recombinants between these loci have been detected in the 248 animals; all of the recombinants were screened at the other anchor loci to identify any double crossovers. Pedigree analysis using these recombinants strongly favors a gene order of (Cf-9)-Gabra3-(DXPas8, Bpa)-CamL1-(Rsvp, P3, Cf-8)-Dmd for the loci studied. Synteny with human Xq27-Xq28 is retained, although the relative order of some loci may differ between the two species. |
