First Author | Laval SH | Year | 1991 |
Journal | Genomics | Volume | 10 |
Issue | 4 | Pages | 1030-4 |
PubMed ID | 1916808 | Mgi Jnum | J:11472 |
Mgi Id | MGI:59905 | Doi | 10.1016/0888-7543(91)90194-j |
Citation | Laval SH, et al. (1991) The properdin structural locus (Pfc) lies close to the locus for tissue inhibitor of metallothionine proteases (Timp) on the mouse X chromosome. Genomics 10(4):1030-4 |
abstractText | We have confirmed the assignment of the structural locus of the complement factor properdin (Pfc) to the mouse X chromosome and mapped it between monoamine oxidase-A (Mao-a) and hypoxanthine phosphoribosyltransferase (Hprt) using a Mus spretus x Mus musculus interspecific backcross of 108 animals. The structural locus for murine tissue inhibitor of metallothionine proteases (Timp) could not be separated from properdin in a panel of 18 recombinant animals. By minimizing the number of double recombinants the following gene order was obtained: Otc-Mao-a-(Pfc, Timp)-Hprt-Cf-9. The implications for comparative mapping of human and mouse X chromosomes are discussed. |