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Publication : Analysis of Ly5 chromosome 1 position using allelic differences and recombinant inbred mice.

First Author  Zebedee SL Year  1991
Journal  Eur J Immunogenet Volume  18
Issue  3 Pages  155-63
PubMed ID  1834169 Mgi Jnum  J:658
Mgi Id  MGI:49194 Doi  10.1111/j.1744-313x.1991.tb00015.x
Citation  Zebedee SL, et al. (1991) Analysis of Ly5 chromosome 1 position using allelic differences and recombinant inbred mice. Eur J Immunogenet 18(3):155-63
abstractText  Differences between the mouse Ly5a and Ly5b alleles can be distinguished on the basis of polymerase chain reaction (PCR)-restriction enzyme analysis and differential monoclonal antibody reactivities. To more precisely map the Ly5 gene on the mouse chromosome 1, analytical DNA and protein tests were performed on recombinant inbred strains of mice prepared from SJL/J (Ly5a) and BALB/cke (Ly5b) progenitor strains. Each recombinant inbred strain was characterized to determine whether it carried the Ly5a or Ly5b allele. Both assays, DNA-PCR and protein-immunofluorescence, yielded identical results for each strain examined. Placement of the Ly5 gene with respect to other characterized markers of mouse chromosome 1 for these recombinant inbred mouse strains shows a gene order of Idh-1:Ity:Pep3:[Ly5, Cfh].
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