| First Author | Bahary N | Year | 1991 |
| Journal | Genomics | Volume | 11 |
| Issue | 1 | Pages | 33-47 |
| PubMed ID | 1684952 | Mgi Jnum | J:3321 |
| Mgi Id | MGI:51834 | Doi | 10.1016/0888-7543(91)90099-z |
| Citation | Bahary N, et al. (1991) Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics 11(1):33-47 |
| abstractText | We have generated a moderate resolution genetic map of mouse chromosomes 4 and 6 utilizing a (C57BL/6J x Mus spretus) F1 x Mus spretus backcross with RFLPs for 31 probes. The map for chromosome 4 covers 77 cM and details a large region of homology to human chromosome 1p. The map establishes the breakpoints in the mouse 4-human 1p region of homology to a 2-cM interval between Ifa and Jun in mouse and to the interval between JUN and ACADM in human. The map for mouse chromosome 6 spans a 65-cM region and contains a large region of homology to human 7q. These maps also provide chromosomal assignment and order for a number of previously unmapped probes. The maps should allow the rapid regional assignment of new markers to mouse chromosomes 4 and 6. In addition, knowledge of the gene order in mouse may prove useful in determining the gene order of the homologous regions in human. |
