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Publication : The syntenic relationship between the critical deletion region for the Prader-Willi/Angelman syndromes and proximal mouse chromosome 7.

First Author  Chaillet JR Year  1991
Journal  Genomics Volume  11
Issue  3 Pages  773-6
PubMed ID  1685485 Mgi Jnum  J:11587
Mgi Id  MGI:59998 Doi  10.1016/0888-7543(91)90090-2
Citation  Chaillet JR, et al. (1991) The syntenic relationship between the critical deletion region for the Prader-Willi/Angelman syndromes and proximal mouse chromosome 7. Genomics 11(3):773-6
abstractText  The deleted region of the proximal long arm of human chromosome 15, common to a large group of patients with the Prader-Willi and Angelman syndromes, has recently been defined. We have mapped to the mouse genome segments homologous to human probes found within and flanking this deletional region. These probes define a region of conserved synteny on proximal chromosome 7 of the mouse. Because the Prader-Willi and Angelman syndromes are postulated to result from genomic imprinting within the common deletion, these probes may define a genomically imprinted region on mouse chromosome 7.
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