First Author | Chaillet JR | Year | 1991 |
Journal | Genomics | Volume | 11 |
Issue | 3 | Pages | 773-6 |
PubMed ID | 1685485 | Mgi Jnum | J:11587 |
Mgi Id | MGI:59998 | Doi | 10.1016/0888-7543(91)90090-2 |
Citation | Chaillet JR, et al. (1991) The syntenic relationship between the critical deletion region for the Prader-Willi/Angelman syndromes and proximal mouse chromosome 7. Genomics 11(3):773-6 |
abstractText | The deleted region of the proximal long arm of human chromosome 15, common to a large group of patients with the Prader-Willi and Angelman syndromes, has recently been defined. We have mapped to the mouse genome segments homologous to human probes found within and flanking this deletional region. These probes define a region of conserved synteny on proximal chromosome 7 of the mouse. Because the Prader-Willi and Angelman syndromes are postulated to result from genomic imprinting within the common deletion, these probes may define a genomically imprinted region on mouse chromosome 7. |