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Publication : New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions.

First Author  Ollendorff V Year  1992
Journal  Mamm Genome Volume  2
Issue  3 Pages  195-200
PubMed ID  1543912 Mgi Jnum  J:2352
Mgi Id  MGI:50876 Doi  10.1007/BF00302877
Citation  Ollendorff V, et al. (1992) New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions. Mamm Genome 2(3):195-200
abstractText  Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies in which most of the key genes remain to be identified. In an effort to isolate as many candidates as possible, we are cloning genes from this region. We report here the mapping of a new sequence from 11q13.5-11q14. This sequence, designated D11S833E, putatively encodes a new gene, provisionally named GARP. We cloned its homologous sequence in the mouse and located it on Chromosome (Chr) 7, region F. The human and mouse genes belong to a conserved group of synteny. This, together with the similar conservation of the FGF and TYR genes, indicates that the human 11q13-q14 and mouse 7E-7F regions share homology.
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