| First Author | Sequeira A | Year | 1992 |
| Journal | Mol Immunol | Volume | 29 |
| Issue | 3 | Pages | 425-30 |
| PubMed ID | 1557049 | Mgi Jnum | J:1798 |
| Mgi Id | MGI:50322 | Doi | 10.1016/0161-5890(92)90030-2 |
| Citation | Sequeira A, et al. (1992) Characterization of a murine immunoglobulin VH gene segment in subgroup III: a new member of the 7183 gene family. Mol Immunol 29(3):425-30 |
| abstractText | A new gene for the variable region of the immunoglobulin heavy chain (VH gene) has been isolated from BALB/c adult liver DNA using a cDNA plasmid probe containing a mouse VH sequence. The complete nucleotide sequence of this germline gene (VH10-19), shows that it belongs to the 7183 gene family. The VH gene appears to contain an intervening 104-base-long sequence and displays the same recombination signal sequences that those observed in the germline 81X. The presence of an internal heptamer at the 3' end of the VH10-19 coding region let an alternative recombination event that could increase the representation of this gene in the immature repertoire. |
