| First Author | Manova K | Year | 1992 |
| Journal | Mech Dev | Volume | 36 |
| Issue | 3 | Pages | 141-52 |
| PubMed ID | 1373953 | Mgi Jnum | J:1989 |
| Mgi Id | MGI:50513 | Doi | 10.1016/0925-4773(92)90065-r |
| Citation | Manova K, et al. (1992) Expression of activins and TGF beta 1 and beta 2 RNAs in early postimplantation mouse embryos and uterine decidua. Mech Dev 36(3):141-52 |
| abstractText | The expression of the mesoderm inducing factors, activins and TGF beta s, was characterized in 5 1/2-9 1/2 day mouse embryos and implantation sites by in situ hybridization. Activin beta A RNA was not detected within the embryo, but is expressed in nearby decidual cells from 5 to 7 days. Thus activin A could play a role within the embyro during gastrulation. Activin beta A is also expressed in more mesometrially located decidual cells from 6 to 9 1/2 days. Activin beta B and inhibin alpha RNAs were not detected, while a control tissue was highly positive. TGF beta 1 is expressed in the secondary decidual zone and in developing endothelial cells in the decidua and embryo. TGF beta 2 is expressed in the mesometrial decidua at 6 1/2 days and in the midline of the cranial neural plate. |
