| First Author | Tucker PK | Year | 1992 |
| Journal | Mamm Genome | Volume | 3 |
| Issue | 5 | Pages | 254-61 |
| PubMed ID | 1353382 | Mgi Jnum | J:1299 |
| Mgi Id | MGI:49829 | Doi | 10.1007/bf00292153 |
| Citation | Tucker PK, et al. (1992) Geographic origin of the Y chromosomes in old inbred strains of mice. Mamm Genome 3(5):254-61 |
| abstractText | Six distinct Y Chromosomes (Chr) were identified among 39 standard inbred strains of mice with five probes that identified Y Chr-specific restriction fragments on Southern blots. Three Y Chr types, distributed among 31 strains, were of Asian Mus musculus origin. The remaining three Y Chr types, distributed among eight strains, were of M. domesticus origin. The Asian source of the M. musculus Y Chr was confirmed by determining the DNA sequence of 221 bp from an open reading frame within the Sry (sex determining region Y) gene (Gubbay et al., Nature 346: 245-250, 1990) in three inbred strains (C57BL/6J, AKR/J, and SWR/J) and comparing the sequence to the homologous sequences derived from wild caught European and Asian M. musculus males. These data indicate that a minimum of six male mice contributed to the formation of the old inbred strains. |
