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Publication : Renal involvement in mice experimentally infected with Toxocara canis embryonated eggs.

First Author  Casarosa L Year  1992
Journal  Vet Parasitol Volume  42
Issue  3-4 Pages  265-72
PubMed ID  1496786 Mgi Jnum  J:3248
Mgi Id  MGI:60065 Doi  10.1016/0304-4017(92)90068-k
Citation  Casarosa L, et al. (1992) Renal involvement in mice experimentally infected with Toxocara canis embryonated eggs. Vet Parasitol 42(3-4):265-72
abstractText  Histological examination of kidneys from mice experimentally infected with Toxocara canis embryonated eggs demonstrated the presence of a segmental or diffuse mesangioproliferative glomerulonephritis. Immunohistochemical studies established that renal alterations were associated with glomerular deposits of IgG, IgM and third component of complement (C3). These findings suggest that an immunomediated mechanism might possibly be involved in the genesis of kidney damage observed in mice infected with T. canis embryonated eggs.
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