| First Author | Seldin MF | Year | 1992 |
| Journal | Cytogenet Cell Genet | Volume | 60 |
| Issue | 3-4 | Pages | 252-4 |
| PubMed ID | 1354597 | Mgi Jnum | J:2075 |
| Mgi Id | MGI:50599 | Doi | 10.1159/000133352 |
| Citation | Seldin MF, et al. (1992) Localization of mouse parathyroid hormone-like peptide gene (Pthlh) to distal chromosome 6 using interspecific backcross mice and in situ hybridization. Cytogenet Cell Genet 60(3-4):252-4 |
| abstractText | The single copy parathyroid hormone-like peptide gene (Pthlh) was mapped to distal mouse chromosome 6 using genetic linkage analysis with a panel of DNA samples from interspecific backcross mice. In all 114 meiotic events examined, the Pthlh locus cosegregated with the locus for the Kirsten ras-2 gene (Kras-2) which was previously localized to distal mouse chromosome 6. In addition, Pthlh was localized to chromosome 6 band F-G and the mouse parathyroid hormone Pth was localized to chromosome 7 band F, by in situ hybridization. These studies confirm the previous localization of Pthlh to mouse chromosome 6 using somatic cell hybrids and show that the Pthlh/PTHLH locus is a part of a conserved linkage group between distal mouse chromosome 6 and the proximal segment of the short arm of human chromosome 12. |
