| First Author | Anand R | Year | 1992 |
| Journal | Genomics | Volume | 13 |
| Issue | 4 | Pages | 962-7 |
| PubMed ID | 1505988 | Mgi Jnum | J:1668 |
| Mgi Id | MGI:50194 | Doi | 10.1016/0888-7543(92)90008-g |
| Citation | Anand R, et al. (1992) Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans. Genomics 13(4):962-7 |
| abstractText | We have determined the chromosomal location of seven human neuronal nicotinic acetylcholine receptor subunit genes by genomic Southern analysis of hamster/human somatic cell hybrid DNAs. The beta 2 subunit gene was localized to human chromosome 1, the alpha 2 and beta 3 subunit genes were localized to human chromosome 8, the alpha 3, alpha 5, and beta 4 subunit genes were localized to human chromosome 15, and the alpha 4 subunit gene was localized to human chromosome 20. Mapping of the beta 2 subunit gene to chromosome 1 establishes a syntenic group with the amylase gene locus on human chromosome 1 and mouse chromosome 3, while mapping of the alpha 3 subunit gene to chromosome 15 confirms the existence of a syntenic group with the mannose phosphate isomerase gene locus on human chromosome 15 and mouse chromosome 9. |
