First Author | Weydert A | Year | 1992 |
Journal | C R Acad Sci III | Volume | 314 |
Issue | 10 | Pages | 429-35 |
PubMed ID | 1521164 | Mgi Jnum | J:1641 |
Mgi Id | MGI:50168 | Citation | Weydert A, et al. (1992) Molecular cloning of two partial serotonin 5-HT1D receptor sequences in mouse and one in guinea pig. C R Acad Sci III 314(10):429-35 |
abstractText | The G protein coupled serotonin (5-HT) receptors, with seven membrane spanning domains, form a multigene family of which several members have been cloned and sequenced. The presence of 5-HT1D binding sites to our knowledge has not yet been reported in mouse. Here we describe the cloning and sequencing by the polymerase chain reaction (PCR) method of two 5-HT1D receptor sequences of the third cytoplasmic loop in mouse, strongly suggesting the existence of two 5-HT1D receptor genes, located on chromosome 4. A homologous sequence to one of them was cloned in guinea pig. |