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Publication : Molecular cloning of two partial serotonin 5-HT1D receptor sequences in mouse and one in guinea pig.

First Author  Weydert A Year  1992
Journal  C R Acad Sci III Volume  314
Issue  10 Pages  429-35
PubMed ID  1521164 Mgi Jnum  J:1641
Mgi Id  MGI:50168 Citation  Weydert A, et al. (1992) Molecular cloning of two partial serotonin 5-HT1D receptor sequences in mouse and one in guinea pig. C R Acad Sci III 314(10):429-35
abstractText  The G protein coupled serotonin (5-HT) receptors, with seven membrane spanning domains, form a multigene family of which several members have been cloned and sequenced. The presence of 5-HT1D binding sites to our knowledge has not yet been reported in mouse. Here we describe the cloning and sequencing by the polymerase chain reaction (PCR) method of two 5-HT1D receptor sequences of the third cytoplasmic loop in mouse, strongly suggesting the existence of two 5-HT1D receptor genes, located on chromosome 4. A homologous sequence to one of them was cloned in guinea pig.
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