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Publication : Auditory brainstem function of the F1 offspring of the cross of CBA/CaJ and AU/SsJ inbred mice.

First Author  Henry KR Year  1992
Journal  Audiology Volume  31
Issue  4 Pages  190-5
PubMed ID  1444930 Mgi Jnum  J:2853
Mgi Id  MGI:51373 Doi  10.3109/00206099209081654
Citation  Henry KR, et al. (1992) Auditory brainstem function of the F1 offspring of the cross of CBA/CaJ and AU/SsJ inbred mice. Audiology 31(4):190-5
abstractText  Inbred strains of laboratory mice have several distinct advantages as models for examining conditions that influence the human auditory system, but the CBA/J mouse which has most often been used as a normal model has recently been found to have several disadvantages. This paper is the first report of the auditory brainstem responses (ABRs) of the F1 offspring of CBA/CaJ and AU/SsJ parents. At midlife, high-frequency ABR thresholds are lower in the F1 than in either parental genotype. Tuning curves obtained by forward masking of the ABR also display heterosis, i.e. they are narrower in the F1 than in either parental strain.
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