| First Author | Alonso S | Year | 1993 |
| Journal | Mamm Genome | Volume | 4 |
| Issue | 1 | Pages | 15-20 |
| PubMed ID | 8422497 | Mgi Jnum | J:3743 |
| Mgi Id | MGI:52252 | Doi | 10.1007/BF00364657 |
| Citation | Alonso S, et al. (1993) Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1. Mamm Genome 4(1):15-20 |
| abstractText | We present here the genetic mapping of the alpha-skeletal actin locus (Actsk-1) on mouse Chromosome (Chr) 8, on the basis of the PCR analysis of a microsatellite in an interspecific backcross. Linkage and genetic distances were established for four loci by analysis of 192 (or 222) meiotic events and indicated the following gene order: (centromere)-Es-1-11.7 cM-Tat-8.3 cM-Actsk-1-0.5 cM-Aprt. Mapping of ACTSK to human Chr 1 and of TAT and APRT to human Chr 16 demonstrates the existence of a new short region of homology between mouse Chr 8 and human Chr 1. Intermingling on this scale between human and mouse chromosomal homologies that occurred during evolution creates disorders in comparative linkage studies. |
