| First Author | Asano M | Year | 1992 |
| Journal | Mech Dev | Volume | 39 |
| Issue | 1-2 | Pages | 29-39 |
| PubMed ID | 1283313 | Mgi Jnum | J:3679 |
| Mgi Id | MGI:52188 | Doi | 10.1016/0925-4773(92)90023-d |
| Citation | Asano M, et al. (1992) Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development. Mech Dev 39(1-2):29-39 |
| abstractText | The murine paired-box-containing gene 5, Pax-5, is highly homologous to two other Pax genes, Pax-2 and Pax-8. The expression pattern of Pax-5 during mouse embryogenesis was examined by in situ RNA hybridization and compared to those of Pax-2 and Pax-8. Beginning at day 9.5 postcoitum (p.c.), Pax-5 was expressed in the developing brain, predominantly at the midbrain-hindbrain boundary, and in the neural tube. While the neural tube expression pattern overlapped completely with Pax-2 and Pax-8, the expression pattern in the brain was only partially overlapping. Unlike Pax-2 and Pax-8, Pax-5 was not expressed in the developing excretory system, thyroid, eye or ear. Our data suggest that Pax-5 has a role in the development of the central nervous system. |
