| First Author | Pilz AJ | Year | 1993 |
| Journal | Mamm Genome | Volume | 4 |
| Issue | 2 | Pages | 78-82 |
| PubMed ID | 8431641 | Mgi Jnum | J:3880 |
| Mgi Id | MGI:52385 | Doi | 10.1007/BF00290430 |
| Citation | Pilz AJ, et al. (1993) Mapping of the human homologs of the murine paired-box-containing genes. Mamm Genome 4(2):78-82 |
| abstractText | Mutations in paired-box-containing (Pax) genes have recently been found to be the primary lesions underlying human genetic disorders such as Waardenburg's Syndrome type 1 and mouse developmental mutants such as undulated (un), splotch (Sp), and small eye (Sey). In addition, PAX-6 is a strong candidate gene for aniridia in man. Eight independent Pax genes have been isolated in the mouse. All eight map to distinct regions of the mouse genome; they do not appear to be clustered in the same way as some groups of homeobox-containing genes. We have now mapped the human homologs of all eight of these genes; PAX genes are found on human Chromosomes (Chr) 1, 2, 7, 9, 10, 11, and 20. |
