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Publication : Mapping of a rat multidrug resistance gene by fluorescence in situ hybridization.

First Author  Popescu NC Year  1993
Journal  Genomics Volume  15
Issue  1 Pages  182-4
PubMed ID  8094367 Mgi Jnum  J:3826
Mgi Id  MGI:52334 Doi  10.1006/geno.1993.1028
Citation  Popescu NC, et al. (1993) Mapping of a rat multidrug resistance gene by fluorescence in situ hybridization. Genomics 15(1):182-4
abstractText  A cDNA clone encoding the rat mdr1b (Pgy2) gene was recently isolated and characterized. This gene has a high degree of sequence identity with other Pgy genes, particularly the mouse Pgy2 gene. By means of in situ fluorescence hybridization, the rat Pgy gene was localized on chromosome 4 band q12. This regional mapping will facilitate the identification of synteny groups on rat, mouse, and human genomes and chromosomal rearrangements during mammalian evolution.
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