| First Author | Virtaneva KI | Year | 1993 |
| Journal | Immunogenetics | Volume | 37 |
| Issue | 6 | Pages | 461-5 |
| PubMed ID | 8436422 | Mgi Jnum | J:4314 |
| Mgi Id | MGI:52810 | Doi | 10.1007/BF00222471 |
| Citation | Virtaneva KI, et al. (1993) The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes. Immunogenetics 37(6):461-5 |
| abstractText | CD37, CD53, and R2 leukocyte surface antigens are members of a novel family of structurally related proteins. They all have four transmembrane-spanning domains with a single major extracellular loop. The CD37 is expressed on B cells and on a subpopulation of T cells. The CD53 is known as a panleukocyte marker. The R2 protein is an activation antigen of T cells. The CD37, CD53, and R2 genes were assigned with the help of human/rodent somatic cell hybrids and human-specific probes to human chromosomes 19, 1, and 11, respectively. For the regional assignment, various deletion hybrids were used to map CD37 to 19p13-q13.4, CD53 to 1p12-p31, and R2 to 11p12. |
